Symbol
Name
ID

Pkd1
polycystin 1, transient receptor potential channel interacting
MGI:97603

Phenotype annotations related to endocrine/exocrine glands

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Pancreatic cysts	Pituitary growth hormone cell adenoma
Disease(s) Associated with PKD1	Pancreatic cysts	Pituitary growth hormone cell adenoma
autosomal dominant polycystic kidney disease

Mouse Phenotypes

abnormal exocrine pancreas morphology

abnormal pancreatic acinus morphology

dilated pancreatic duct

exocrine pancreas atrophy

endocrine/exocrine gland phenotype

abnormal bile duct morphology

abnormal common bile duct morphology

biliary cyst

dilated bile duct

decreased pancreatic islet number

enlarged pancreas

pancreas cyst

pancreas fibrosis

pancreas lipomatosis

increased activity of parathyroid

Availability

Mouse Genotype

Pkd1^m1Bei/Pkd1^m1Bei

Pkd1^tm1.1Fqi/Pkd1^tm1.1Fqi

Pkd1^tm1Bdgz/Pkd1^tm1Bdgz

Pkd1^tm1Djmp/Pkd1^tm1Djmp

Pkd1^tm1Ggg/Pkd1^tm1Ggg

Pkd1^tm1Hung/Pkd1^tm1Hung

Pkd1^tm1Jzh/Pkd1^tm1Jzh

Pkd1^tm1Maa/Pkd1^tm1Maa

Pkd1^tm1Som/Pkd1^tm1Som

Pkd1^tm2.1Ggg/Pkd1^tm2.1Ggg

Pkd1^tm2Jzh/Pkd1^tm2Jzh

Pkd1^tm1Bdgz/Pkd1⁺

Pkd1^tm1Jzh/Pkd1⁺

Pkd1^tm1Shh/Pkd1^tm1.1Pcha

Pkd1^tm2Jzh/Pkd1⁺

Pkd1^tm2Ggg/Pkd1^tm2Ggg
Tg(Col1a1-cre)1Bek/0 (conditional)

Pkd1^tm2Ggg/Pkd1⁺
Tg(Col1a1-cre)1Bek/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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